N-(5-Hydroxypentyl)maleimide 是一种不可降解 (non-cleavable) 的 ADC linker,可用于合成抗体偶联药物 (ADC),例如 Gemcitabine-O-Si(di-iso)-O-Mc (HY-130812)。
生物活性 | N-(5-Hydroxypentyl)maleimide is anon-cleavableADC linker used in the synthesis ofantibody-drug conjugates (ADCs), such as Gemcitabine-O-Si(di-iso)-O-Mc (HY-130812) )[1]. |
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体外研究 (In Vitro) | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker)[1].
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运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | -20°C, stored under nitrogen *In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen) |