Luteolin 7-sulfate 是从海生植物 Phyllospadix iwatensis Makino 中分离出来的。 Luteolin 7-sulfate 通过 cAMP 反应元件结合蛋白 (CREB) 和小眼症相关转录因子 (MITF) 介导的信号通路的干预减弱 TYR 基因表达，从而导致黑色素合成减少。
| Cas No. | 56857-57-9 |
| 别名 | 木犀草素-7-硫酸酯 |
| Canonical SMILES | O=C1C2=C(O)C=C(OS(=O)(O)=O)C=C2OC(C3=CC(O)=C(O)C=C3)=C1 |
| 分子式 | C15H10O9S |
| 分子量 | 366.3 |
| 溶解度 | Soluble in DMSO |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Luteolin 7-sulfate is isolated from Phyllospadix iwatensis Makino, a marine plant. Luteolin 7-sulfate attenuates TYR gene expression through the intervention of a cAMP-responsive element binding protein (CREB)- and microphthalmia-associated transcription factor (MITF)-mediated signaling pathway, leading to the decreased melanin synthesis[1]. [1]. Lee SW, et al. Luteolin 7-Sulfate Attenuates Melanin Synthesis through Inhibition of CREB- and MITF-Mediated Tyrosinase Expression. Antioxidants (Basel). 2019 Apr 4;8(4). |
