16α-羟基泼尼松龙是糖皮质激素布地奈德的 22(R) 差向异构体通过细胞色素 P450 3A (CYP3A) 酶产生的立体选择性代谢物。
| Cas No. | 13951-70-7 |
| 别名 | 16alpha-羟基泼尼松龙,OH-PRED |
| Canonical SMILES | [H][C@]12[C@@]([C@@](C[C@@H](O)[C@]3(O)C(CO)=O)([H])[C@]3(C)C[C@@H]2O)([H])CCC4=CC(C=C[C@@]41C)=O |
| 分子式 | C21H28O6 |
| 分子量 | 376.4 |
| 溶解度 | DMF: 30 mg/mL,DMSO: 30 mg/mL,Ethanol: 30 mg/mL,Ethanol:PBS (pH 7.2) (1:4): 0.2 mg/mL |
| 储存条件 | 4°C, protect from light |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | 16α-hydroxy Prednisolone is a stereoselective metabolite of the 22(R) epimer of the glucocorticoid budesonide. It is formed via metabolism of 22(R)-budesonide by the cytochrome P450 (CYP) isoform CYP3A. |
