Tetraethylene glycol monotosylate 是一种可降解 (cleavable) 的基于酰基腙的ADC linker,用于合成抗体偶联药物 (ADCs)。Tetraethylene glycol monotosylate 也可用作 PROTAC 的 Linker,可用于 PROTAC 的合成。
生物活性 | Tetraethylene glycol monotosylate is acleavableand acylhydrazone-basedADC linkerused in the synthesis ofantibody-drug conjugates (ADCs)[1]. Tetraethylene glycol monotosylate also can be used as aPROTAClinker that can be used in the synthesis ofPROTACs. |
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体外研究 (In Vitro) | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
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运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Pure form | -20°C | 3 years | | 4°C | 2 years | In solvent | -80°C | 6 months | | -20°C | 1 month |
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