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Propofolβ-D-Glucuronide
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Propofolβ-D-Glucuronide图片
CAS NO:114991-26-3
包装与价格：
包装价格(元)
500μg询价
1mg询价
5mg询价
10mg询价

Cas No.114991-26-3
别名2,6-二异丙基Β-D-吡喃葡萄糖酸
化学名2,6-bis(1-methylethyl)phenylβ-D-glucopyranosiduronic acid
Canonical SMILESCC(C)C1=CC=CC(C(C)C)=C1O[C@@H]2O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]2O
分子式C18H26O7
分子量354.4
溶解度30mg/mL in DMSO, 30mg/mL in DMF, 30mg/mL in Ethanol
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Propofol β-D-glucuronide is a metabolite of propofol sulfate , a short-acting anesthetic agent. [1] [2] The metabolite is generated through the glucuronidation of propofol by uridine diphosphate glucuronosyltransferases. Propofol metabolism appears to occur more rapidly in women than men. [1]

Reference:
[1]. Choong, E., Loryan, I., Lindqvist, M., et al. Sex difference in formation of propofol metabolites: A replication stud. Basic Clin.Pharmacol.Toxicol. 113(2), 126-131 (2013).
[2]. Sorensen, L.K., and Hasselstrom, J.B. Simultaneous determination of propofol and its glucuronide in whole blood by liquid chromatography-electrospray tandem mass spectrometry and the influence of sample storage conditions on the reliability of the test results. J.Pharm.Biomed.Anal. 109, (2015).

 
 
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