CAS NO: | 756526-03-1 |
生物活性 | Bis-PEG5-NHS ester is a PEG/Alkyl/ether-basedPROTAClinkercan be used in the synthesis ofPROTACs. Bis-PEG5-NHS ester is acleavableADC linkerused in the synthesis ofantibody-drug conjugates (ADCs)[1]. | |||||||||
IC50& Target[1] |
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体外研究 (In Vitro) | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. | |||||||||
分子量 | 532.50 | |||||||||
性状 | Viscous liquid | |||||||||
Formula | C22H32N2O13 | |||||||||
CAS 号 | 756526-03-1 | |||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | |||||||||
储存方式 |
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