Morinidazole R 对映异构体 (R-Morinidazole) 是一种具有口服活性的 5-硝基咪唑抗菌剂,可通过 N+- 葡萄糖醛酸化和硫酸化在人体中进行广泛代谢。
Cas No. | 898230-59-6 |
别名 | R-吗啉硝唑 |
Canonical SMILES | O[C@@H](CN1C([N+]([O-])=O)=CN=C1C)CN2CCOCC2 |
分子式 | C11H18N4O4 |
分子量 | 270.29 |
溶解度 | DMSO : ≥ 100 mg/mL (369.97 mM) |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Morinidazole R enantiomer is the R-enantiomer of Morinidazole. Morinidazole is a new 5-nitroimidazole class antimicrobial agent. Morinidazole R enantiomer is the less active enantiomer. [1]. Zhong K, et al. Effects of renal impairment on the pharmacokinetics of morinidazole: uptake transporter-mediated renal clearanceof the conjugated metabolites. Antimicrob Agents Chemother. 2014 Jul;58(7):4153-61. |