Artemotil (β-Arteether) (β-Arteether) 具有抗疟活性，用于治疗耐氯喹的恶性疟原虫疟疾，IC50 为 1.61 nM。
| Cas No. | 75887-54-6 |
| 别名 | 蒿乙醚; β-Arteether; (+)-Arteether; Arteether |
| Canonical SMILES | C[C@@H]1[C@@](CC[C@@H](C)[C@]2([H])CC[C@]3(C)O4)([H])[C@@]2(OO3)[C@]4([H])O[C@@H]1OCC |
| 分子式 | C17H28O5 |
| 分子量 | 312.4 |
| 溶解度 | DMSO : 50 mg/mL (160.05 mM);Water :< 0.1 mg/mL (insoluble) |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Artemotil (β-Arteether) is a fast acting blood schizonticide specifically indicated for the treatment of chloroquine-resistant Plasmodium falciparum malaria and cerebral malaria cases. Target:Artemotil is a semi-synthetic derivative of artemisinin, a natural product of the Chinese plant Artemisia annua. [1]. Looareesuwan S, et al. Dose-finding and efficacy study for i.m. artemotil (beta-arteether) and comparison with i.m. artemether in acute uncomplicated P. falciparum malaria. Br J Clin Pharmacol. 2002 May;53(5):492-500. |
