DM1-PEG4-DBCO

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DM1-PEG4-DBCO

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

DM1-(PEG)4-DBCO 是由微管蛋白抑制剂 DM1 和连接剂 DBCO-PEG4-Ahx 组成的药物偶联物 (ADC)。Mertansin (DM1) 是一种微管蛋白抑制剂，是一种抗体偶联的美登素，是为了克服与美登素有关的全身毒性和增强肿瘤特异性递送而开发的。

生物活性

DM1-(PEG)4-DBCO is a drug-linker conjugate composed of a potent microtubulin inhibitor DM1 and a linker DBCO-PEG4-Ahx to make antibody drug conjugate (ADC). Mertansine (DM1) is a microtubulin inhibitor and is an antibody-conjugatable maytansinoid that is developed to overcome systemic toxicity associated with maytansine and to enhance tumor-specific delivery.

IC₅₀& Target

Maytansinoids

分子量

1198.79

Formula

C₆₃H₈₀ClN₅O₁₆

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.