Mal-PEG4-VC-PAB-DMEA-PNU-159682,一种用于ADC的药物-偶联物,由 ADC 接头 Mal-PEG4-VC-PAB 和有效的 ADC 细胞毒素DMEA-PNU-159682 组成。 DMEA-PNU-159682 包括来自肝微粒体代谢产物的新霉素 (MMDX) 和 ADC 细胞毒素 PNU-159682。
生物活性 | Mal-PEG4-VC-PAB-DMEA-PNU-159682, a drug-linker conjugate forADC, consists theADC linkerMal-PEG4-VC-PAB and a potentADC cytotoxinDMEA-PNU-159682. DMEA-PNU-159682 includes metabolites of nemorubicin (MMDX) from liver microsomes andADC cytotoxinPNU-159682[1]. |
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运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | -20°C, protect from light, stored under nitrogen *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen) |