Deruxtecan analog 2

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Deruxtecan analog 2

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CAS NO:

1599440-10-4

Deruxtecan analog 2 (example 9 P3) 是一种 Deruxtecan (HY-13631E) 类似物。Deruxtecan analog 2 是一种药物-linker 偶联物，由 Camptothecin (HY-16560) 和 linker 组成。Camptothecin (CPT) 是一种 Topo I 抑制剂，对结直肠癌、乳腺癌、肺癌和卵巢癌具有抗肿瘤活性。Deruxtecan analog 2 可用于制备抗-EGFR2 的 ADC 药物。

生物活性	Deruxtecan analog 2 (example 9 P3) is aDeruxtecan(HY-13631E) analog. Deruxtecan analog 2 is adrug-linker conjugatecomposed ofCamptothecin(HY-16560) and a linker. Camptothecin (CPT) is aTopo I inhibitorwith antineoplastic activity against colorectal, breast, lung and ovarian cancers. Deruxtecan analog 2 can be used for the preparation anti-FGFR2 ADC^[1].
分子量	579.58
性状	Solid
Formula	C₂₉H₃₀FN₅O₇
CAS 号	1599440-10-4
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	-20°C, protect from light, stored under nitrogen *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)