DBCO-PEG4-GGFG-Exatecan (DBCO-PEG4-GGFG-DX8951) 是抗体-药物偶联物的一部分，由 DNA 拓扑异构酶 I 抑制剂 DX8951 和可裂解的 ADC linker DBCO-PEG4-GGFG 连接而成。
| 生物活性 | DBCO-PEG4-GGFG-Exatecan (DBCO-PEG4-GGFG-DX8951) is adrug-linker conjugate for ADCwith potent antitumor activity by using DX8951 (a DNAtopoisomeraseI inhibitor), linked via the cleavableADC linkerDBCO-PEG4-GGFG[1]. |
| IC50& Target[1] | Traditional Cytotoxic Agents |
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体外研究
(In Vitro) | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linke[1].
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | -20°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |
