Morinidazole是一种新型的5-硝基咪唑抗菌药,用于治疗细菌感染,包括厌氧菌引起的阑尾炎盆腔炎(PID)。
Cas No. | 92478-27-8 |
别名 | 吗啉硝唑 |
Canonical SMILES | OC(CN1C([N+]([O-])=O)=CN=C1C)CN2CCOCC2 |
分子式 | C11H18N4O4 |
分子量 | 270.29 |
溶解度 | DMSO : ≥ 100 mg/mL (369.97 mM) |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Morinidazole is a novel 5-nitroimidazole antimicrobial drug that undergoes extensive metabolism in humans via N+-glucuronidation and sulfation, for the treatment of bacterial infections including appendicitis and pelvic inflammatory disease (PID) caused by anaerobic bacteria. [1]. Zhong K, et al. Effects of renal impairment on the pharmacokinetics of morinidazole: uptake transporter-mediated renal clearanceof the conjugated metabolites. Antimicrob Agents Chemother. 2014 Jul;58(7):4153-61. |