MMPSI

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MMPSI

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

220509-74-0

MMPSI 是一种有效且具有选择性的caspase 3和caspase 7小分子抑制剂，对人 caspase-3 的IC₅₀为 1.7 μM。MMPSI 能显著减少离体兔心脏缺血再灌注诱导的梗死面积，降低缺血心肌和离体心肌细胞凋亡 (apoptosis)。MMPSI 可用于心脏保护研究。

生物活性

MMPSI is a potent and selective small moleculecaspase 3andcaspase 7inhibitor with anIC₅₀of 1.7 μM for human caspase-3. MMPSI can significantly reduce ischemia-reperfusion-induced infarct size in the isolated rabbit heart, and reduceapoptosisin both the ischemic myocardium and isolated cardiomyocytes. MMPSI can be used for researching cardioprotection^[1].

IC₅₀& Target

human Caspase-3

1.7 μM (IC₅₀)

分子量

324.35

Formula

C₁₄H₁₆N₂O₅S

CAS 号

220509-74-0

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.