PUMA BH3 是一种 p53 正向凋亡调控因子 (PUMA) BH3结构域多肽,作为Bak的直接激活剂,Kd值为 26 nM。
生物活性 | PUMA BH3 is a p53 upregulated modulator ofapoptosis(PUMA) BH3 domain peptide, acts as a direct activator ofBak, with aKdof 26 nM. |
IC50& Target[1] | |
体外研究 (In Vitro) | PUMA BH3 is a p53 upregulated modulator of apoptosis (PUMA) BH3 domain peptide, acts as a direct activator of Bak, with a Kdof 26 nM. PUMA BH3 binds Bak in the canonical BH3-binding groove, and activates Bak[1].
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Formula | |
Sequence Shortening | EEQWAREIGAQLRRMADDLNAQYER |
运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |