AZD-5991 S-enantiomer 是 AZD-5991 的低活性 S 型对映体。AZD-5991 S-enantiomer 是一种Mcl-1抑制剂,FRET 实验检测的IC50为 6.3 μM,SPR 实验检测的Kd为 0.98 μM。
生物活性 | AZD-5991 S-enantiomer is the less active enantiomer of AZD-5991. AZD-5991 S-enantiomer is aMcl-1inhibitor with anIC50of 6.3 μM in FRET assay and aKdof 0.98 μM in surface plasmon resonance (SPR) assay. |
IC50& Target[1] | Mcl-1 6.3 μM (IC50) | Mcl-1 0.98 μM (Kd) |
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运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |