Mcl1-IN-9 是一种有效的髓细胞白血病基因 1(Mcl-1)抑制剂，在重组的 BCR-ABL+ B-ALL 细胞中的IC50值为 446 nM，Ki值为 0.03 nM。
| 生物活性 | Mcl1-IN-9 is a potentmyeloid cell leukemia-1 (Mcl-1)Inhibitor with anIC50of 446 nM in reengineered BCR-ABL+ B-ALL cells and aKiof 0.03 nM[1]. |
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体外研究
(In Vitro) | Mcl1-IN-9 inhibits growth of Mcl-1 dependent tumor cell lines in the nanomolar range[1].
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体内研究
(In Vivo) | Mcl1-IN-9 inhibits the growth of hematological and triple negative breast cancer xenografts at well tolerated doses[1].
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
