Boc-Asp(OME)-Fluoromethyl Keton 是一种广泛的 caspase 抑制剂，可抑制 Fas 介导的吞噬作用和氧化破裂抑制，但不影响 IL-8 的趋化活性。
| 生物活性 | Boc-Asp(OME)-Fluoromethyl Ketone is a broad rangecaspase inhibitorthat inhibits Fas-mediated phagocytosis and oxidative rupture inhibition, but does not affect the chemotactic activity ofIL-8[1][2]. |
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体外研究
(In Vitro) | Boc-Asp(OME)-Fluoromethyl Keton (100 μM; 30 minutes; Polymorphonuclear leukocytes) prevents Fas-induced and spontaneous apoptosis (–CH-11)[1]. Boc-Asp(OME)-Fluoromethyl Keton (20 μM; 5 hours; J774.1/JA-4 cells) significantly increases LDH release[2].
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
