Sodium Camptothecin

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Sodium Camptothecin

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CAS NO:

25387-67-1

喜树碱钠盐

Sodium Camptothecin 是一种具有抗肿瘤活性的植物生物碱。Sodium Camptothecin 是一种可逆的 RNA 合成 (RNA synthesis) 抑制剂。Sodium Camptothecin 是一种有效的腺病毒复制抑制剂。Sodium Camptothecin 能抑制 DNA 合成 (DNA synthesis)，并引起细胞内预形成的病毒 DNA 断裂。

生物活性	Sodium Camptothecin is a plant alkaloid, with antitumor activity. Sodium Camptothecin is a reversible inhibitor ofRNA synthesis. Sodium Camptothecin is an effective inhibitor of adenovirus replication. Sodium Camptothecin inhibitsDNA synthesisand causes breaks in intracellular preformed viral DNA^[1]^[2].
体外研究 (In Vitro)	Sodium Camptothecin (5 μM; 10 min) causes a severe inhibition of heterogeneously sedimenting nuclear RNA (HnRNA) synthesis^[1]. Sodium Camptothecin also blocks a specific step in the processing of ribosomal precursor RNA, allowing the conversion of 45S RNA to 32S RNA, but inhibiting the conversion of 32S RNA to 28S RNA^[1].
分子量	388.35
Formula	C₂₀H₁₇N₂NaO₅
CAS 号	25387-67-1
中文名称	喜树碱钠盐
结构分类	Alkaloids Quinoline Alkaloids Alkaloids Pyrrole Alkaloids
来源	Plants Nyssaceae Camptotheca acuminataDecne.
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.