CAS NO: | 2378427-68-8 |
生物活性 | Gly-7-MAD-MDCPT (compound 4b) is an anticancer agent. Gly-7-MAD-MDCPT is aCamptothecin(HY-16560) compound, it shows cytotoxicity to variouscancercells withIC50values of 10-1000 nM[1]. |
体外研究 (In Vitro) | Gly-7-MAD-MDCPT (0.1-1000 nM) shows cytotoxic potency to 786-0, BxPC3, HL-60 and SK-MEL-5 with IC50values of 100-1000 nM[1].Gly-7-MAD-MDCPT (0.1-1000 nM) shows cytotoxic potency to L540cy, MM.1R, M0LM13, Ramos, SK-MEL-5, SU-DHL-4 and U266 with IC50values of 10-100 nM[1]. |
分子量 | 478.45 |
性状 | Solid |
Formula | C24H22N4O7 |
CAS 号 | 2378427-68-8 |
运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | 4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |
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