Elomotecan

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Elomotecan

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

220998-10-7

BN 80927 free base

Elomotecan (BN 80927 free base) 是一种有效的拓扑异构酶 I (topoisomerases I) 和II抑制剂。Elomotecan 是属于高喜树碱家族 (hCPT) 的喜树碱类似物。与其他拓扑异构酶 I和II的参考抗癌药物相比，Elomotecan 减少不同肿瘤细胞的增殖效果更好。

生物活性

Elomotecan (BN 80927 free base) is a potent inhibitor oftopoisomerases IandII. Elomotecan is a camptothecin analog belonging to the homocamptothecin family (hCPT). Elomotecan reduces the proliferation of different tumor cells with higher potency than other anticancer drugs of reference targetingtopoisomerases IandII^[1].

IC₅₀& Target^[1]

Topoisomerase I

Topoisomerase II

分子量

522.04

Formula

C₂₉H₃₂ClN₃O₄

CAS 号

220998-10-7

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.