Tipiracil (hydrochloride) is a thymidine phosphorylase inhibitor (TPI), used forcancerresearch.

Tipiracil has antiangiogenic effect, and inhibits proliferation of endothelial cells^[1]. Tipiracil is a potent inhibitor of thymidine phosphorylase, which is the enzyme that degrades FTD^[2].

279.12

Solid

C₉H₁₂Cl₂N₄O₂

183204-72-0

盐酸替吡嘧啶

Room temperature in continental US; may vary elsewhere.

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

H₂O : 50 mg/mL(179.13 mM;Need ultrasonic)

DMF :< 1 mg/mL(insoluble)

DMSO :< 1 mg/mL(insoluble or slightly soluble)

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80℃, 6 months; -20℃, 1 month (sealed storage, away from moisture)。-80℃ 储存时，请在 6 个月内使用，-20℃ 储存时，请在 1 个月内使用。