Apremilast D5 (CC-10004 D5) 是一种 Apremilast 氘代物。Apremilast (CC-10004) 是一种口服有效的磷酸二酯酶 4 (PDE4) 抑制剂，IC50为 74 nM。Apremilast 抑制脂多糖 (LPS) 释放TNF-α，IC50为 104 nM。
| 生物活性 | Apremilast D5 (CC-10004 D5) is a deuterium labeled Apremilast. Apremilast is an orally available inhibitor of type-4 cyclic nucleotidephosphodiesterase(PDE-4) with anIC50of 74 nM. Apremilast inhibits TNF-α release by lipopolysaccharide (LPS) with an IC50of 104 nM[1]. |
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
