PF-06447475 是一种高效、选择性的，可通透血脑屏障的LRRK2激酶抑制剂，针对 WT LRRK 和 G2019S LRRK2 的IC50值分别为 3 nM 和 11 nM。PF-06447475 可用于帕金森病 (PD) 研究。
| 生物活性 | PF-06447475 is a highly potent, selective, brain penetrantLRRK2kinaseinhibitor withIC50values of 3 nM and 11 nM for WT LRRK and G2019SLRRK2, respectively. PF-06447475 can be used for parkinson's disease (PD) research[1]. |
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
