ATR-IN-18 (化合物 2) 是一种口服有效的ATR激酶抑制剂,其IC50为 0.69 nM。ATR-IN-18 在 LoVo 细胞中显示出抗增殖活性,其IC50为 37.34 nM。ATR-IN-18 具有抗肿瘤活性。
| 生物活性 | ATR-IN-18 (compound 2) is an orally active and potentATRkinase inhibitor, with anIC50of 0.69 nM. ATR-IN-18 shows antiproliferative activity in LoVo cells, with anIC50of 37.34 nM. ATR-IN-18 has anti-tumor activity[1]. |
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |