dAURK-4

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dAURK-4

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

2705844-81-9

dAURK-4 是 Alisertib 的一种衍生物，是一种有效的选择性AURKA (Aurora A)降解剂。dAURK-4 具有抗癌作用。

生物活性

dAURK-4, an Alisertib derivative, is a potent and selectiveAURKA (Aurora A)degrader. dAURK-4 has anticancer effects^[1].

IC₅₀& Target^[1]

Aurora A

体外研究
(In Vitro)

dAURK-4 (125-1000 nM; 4-24 hours) shows degradation of AURKA in a dose-depended manner^[1].

Cell Viability Assay^[1]

Cell Line:	MM.1S cells
Concentration:	125 nM, 250 nM, 500 nM, 1000 nM
Incubation Time:	4 hours or 24 hours
Result:	Inhibited the protein level of AURKA (Aurora A).

分子量

1035.47

Formula

C₅₂H₅₂ClFN₈O₁₂

CAS 号

2705844-81-9

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.