CDK7-IN-11

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CDK7-IN-11

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CAS NO:

2414896-32-3

CDK7-IN-11 是一种 CDK7 抑制剂，具有口服活性。CDK7-IN-11 表现出高 CDK7 抑制活性，IC₅₀值为 4.2 nM。CDK7-IN-11 可有效用于 CDK7 相关疾病的研究。

生物活性

CDK7-IN-11 is an orally activeCDK7inhibitor. CDK7-IN-11 exhibits highCDK7inhibitory activity withIC₅₀value of 4.2 nM. CDK7-IN-11 can be effectively used for the research of diseases associated withCDK7^[1].

IC₅₀& Target^[1]

CDK7

4.2 nM (IC₅₀)

体外研究
(In Vitro)

CDK7-IN-11 (example 5) has inhibitory activity for CDK7 with IC₅₀value of 4.2 nM^[1].
CDK7-IN-11 (72 h) inhibits cell proliferation in MDA-MB-468 cells and HepG2 cells with IC₅₀values of 14.0 nM and 3.0 nM^[1].

Cell Proliferation Assay^[1]

Cell Line:	MDA-MB-468 cells, HepG2 cells
Concentration:
Incubation Time:	72 h
Result:	Showed antiproliferative effect in cells.

分子量

488.60

Formula

C₂₆H₂₈N₆O₂S

CAS 号

2414896-32-3

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.