CDK8-IN-10

立即咨询

CDK8-IN-10

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

2457317-40-5

CDK8-IN-10 (compound 2) 是一种有效的选择性细胞周期蛋白依赖性激酶 (CDK8) 抑制剂，其IC₅₀值为 8.25 nM。CDK8-IN-10 可用于癌症的研究。

生物活性

CDK8-IN-10 (compound 2) is a potent, selectivecyclin-dependent kinase(CDK8)inhibitor with anIC₅₀value of 8.25 nM. CDK8-IN-10 can be used for research ofcancer^[1].

IC₅₀& Target^[1]

CDK8

8.25 nM (IC₅₀)

体外研究
(In Vitro)

CDK8-IN-10 (compound 2; 8 h; SW620 cells) reduces phosphorylation of CDK8 substrate STAT1 in cells with an IC₅₀value of 1.3 μM^[1].

分子量

525.87

Formula

C₂₅H₁₅ClF₃N₅O₃

CAS 号

2457317-40-5

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.