FLT3/ITD-IN-4 (Compound 16) 是一种选择性的 FLT3 内部串联重复突变 (FLT3-ITD) 抑制剂，IC50值为 2.3 nM。FLT3/ITD-IN-4 可用于急性骨髓性白血病的研究。
| 生物活性 | FLT3/ITD-IN-4 (Compound 16) is a selective FMS-like tyrosine kinase 3 internal tandem duplications (FLT3-ITD) inhibitor with anIC50of 2.3 nM. FLT3/ITD-IN-4 can be used for acute myeloid leukemia research[1]. |
| IC50& Target | CDK16/Cyclin Y 1768 nM (EC50) | MAP4K4 5737 nM (EC50) | FLT3-ITD 2.3 nM (IC50) | FLT3 D835Y 4.84 nM (IC50) | RET 277 nM (EC50) | FLT3 443 nM (EC50) | ZAK/MLTK 1069 nM (EC50) | DDR2 2494 nM (EC50) | EPHA7 3255 nM (EC50) | NTRK1 3857 nM (EC50) |
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
