维库溴铵 (ORG NC 45) 溴化物是一种非去极化神经肌肉阻滞剂，也可作为烟碱型乙酰胆碱受体 (nAChR) 抑制剂、肌肉松弛剂，可用于术前麻醉。
| Cas No. | 50700-72-6 |
| 别名 | 维库溴铵; ORG NC 45 |
| 化学名 | [(2S,3S,5S,8R,9S,10S,13S,14S,16S,17R)-17-acetyloxy-10,13-dimethyl-16-(1-methylpiperidin-1-ium-1-yl)-2-piperidin-1-yl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl] acetate;bromide |
| Canonical SMILES | CC(=O)OC1CC2CCC3C(C2(CC1N4CCCCC4)C)CCC5(C3CC(C5OC(=O)C)[N+]6(CCCCC6)C)C.[Br-] |
| 分子式 | C34H57N2O4.Br |
| 分子量 | 637.73 |
| 溶解度 | ≥ 31.8865mg/mL in DMSO, ≥ 98.6 mg/mL in EtOH with ultrasonic |
| 储存条件 | Store at 2-8℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Vecuronium bromide is a nondepolarizing neuromuscular blocking agent of intermediate duration. References:
[1]. Meretoja, O.A., Vecuronium infusion requirements in pediatric patients during fentanyl-N2O-O2 anesthesia. Anesth Analg, 1989. 68(1): p. 20-4.
[2]. Agoston, S., et al., The neuromuscular blocking action of ORG NC 45, a new pancuronium derivative, in anaesthetized patients. A pilot study. Br J Anaesth, 1980. 52 Suppl 1: p. 53S-59S.
[3]. Shingu, K., et al., [Neuromuscular blocking effects of Org 9426 (rocuronium bromide); a comparative study with vecuronium bromide in Japanese patients]. Masui, 2006. 55(9): p. 1140-8. |
