CDK4/6-IN-8 (Compound 7p) 是一种选择性的CDK4和CDK6抑制剂，其IC50值分别为 5.01 nM 和 3.97 nM。
| 生物活性 | CDK4/6-IN-8 (Compound 7p) is a selectiveCDK4andCDK6inhibitor withIC50values of 5.01 nM and 3.97 nM, respectively[1]. |
| IC50& Target | CDK4 5.01 nM (IC50) | CDK6 3.97 nM (IC50) |
|
体外研究
(In Vitro) | CDK4/6-IN-8 (Compound 7p) (0-656.1 μM, 48 h) shows anti-breast cancer activity[1].
Cell Viability Assay[1] | Cell Line: | MCF-7 | | Concentration: | 0.1, 0.3, 0.9, 2.7, 8.1, 24.3, 72.9, 218.7 and 656.1 μM | | Incubation Time: | 48 h | | Result: | Inhibited cell viability with an IC50of 2.8 μM. |
|
| 分子量 | |
| Formula | |
| CAS 号 | |
| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
