CDK4/6-IN-12 是一种有效的周期蛋白依赖性激酶 4/6 抑制剂。CDK4/6-IN-12 对 CDK4 和 CDK6 具有酶抑制活性，IC50值分别为 592.3 nM 和 3090 nM。 CDK4/6-IN-12 可用于癌症的研究。
| 生物活性 | CDK4/6-IN-12 is a potentcyclin-dependent kinase4/6 (CDK4/6)inhibitor. CDK4/6-IN-12 has enzymatic inhibitory activity forCDK4andCDK6withIC50of 592.3 nM and 3090 nM, respectively. CDK4/6-IN-12 can be used for the research ofcancer[1]. |
| IC50& Target[1] | CDK4 592.3 nM (IC50) | CDK6 3090 nM (IC50) |
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体外研究
(In Vitro) | CDK4/6-IN-12 (compound 4a) inhibits CDK4 and CDK6 with IC50of 592.3 nM and 3090 nM, respectively[1].
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
