ZDLD20

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ZDLD20

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

2762279-02-5

ZDLD20 是一种 β-咔啉，是一种选择性、具有口服活性的CDK4/CycD3抑制剂，IC₅₀值为 6.51 μM。ZDLD20 表现出有效的抗 HCT116 活性，包括抑制集落形成、抑制侵袭和迁移、诱导细胞凋亡和阻止细胞周期的 G1 期。ZDLD20 表现出有效的抗癌活性。

生物活性

ZDLD20, a β-carboline, is orally active and selectiveCDK4/CycD3inhibitor with anIC₅₀value of 6.51 μM. ZDLD20 exhibits potent anti-HCT116 activity including inhibition of colony formation, inhibition of invasion and migration, inducing ofapoptosis, and arresting of G1 phase in cell cycle. ZDLD20 exhibits potent anticancer activity^[1].

IC₅₀& Target^[1]

CDK4/CycD3

6.51 μM (IC₅₀)

分子量

386.45

Formula

C₂₂H₂₂N₆O

CAS 号

2762279-02-5

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.