Ryuvidine 是一种含有的 SET 结构域的蛋白质 8 (SETD8) 的有效抑制剂，其IC50为 0.5 μM，并在体外抑制 H4K20的甲基化。Ryuvidine 还抑制 CDK4，IC50为 6.0 μM，并对一系列人类癌细胞具有细胞毒性。
| 生物活性 | Ryuvidine is a potent inhibitor ofSET domain-containing protein 8(SETD8)with anIC50of 0.5 μM and suppresses monomethylation of H4K20in vitro[1]. Ryuvidine also inhibitsCDK4with anIC50of 6.0 μM and is cytotoxic against a range of humancancercells[2]. |
| IC50& Target | |
| 分子量 | |
| Formula | |
| CAS 号 | |
| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
