CDK7-IN-6

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CDK7-IN-6

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

2378710-04-2

CDK7-IN-6 是一种有效的选择性细胞周期蛋白依赖性激酶 (CDK7) 抑制剂 (IC₅₀≤100 nM)，来自专利 WO2019197549 A1，compound 210。CDK7- IN-6 对 CDK7 的选择性比 CDK1、CDK2 和 CDK5 高 200 倍以上。CDK7-IN-6 可用于癌症研究。

生物活性

CDK7-IN-6 is a potent and selectivecyclin-dependent kinase(CDK7) inhibitor (IC₅₀≤100 nM), extracted from patent WO2019197549 A1, compound 210. CDK7-IN-6 is >200-fold selective forCDK7overCDK1,CDK2, andCDK5. CDK7-IN-6 can be used for the research ofcancer^[1].

IC₅₀& Target^[1]

CDK7

≤100 nM (IC₅₀)

体外研究
(In Vitro)

CDK7-IN-6 inhibits the viability of HCT116, H460, MV4-11, A2780, and OVCAR cells (IC₅₀≤1 μM)^[1].

分子量

524.06

Formula

C₂₆H₃₄ClN₉O

CAS 号

2378710-04-2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.