CHK1-IN-3 是一种检测点激酶(CHK1)抑制剂，IC50值为 0.4 nM。
| 生物活性 | CHK1-IN-3 is aCheckpoint Kinase 1 (CHK1)inhibitor with anIC50of 0.4 nM[1]. |
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体外研究
(In Vitro) | CHK1-IN-3 effectively inhibites the growth of malignant hematopathy cell lines especially Z-138 (IC50: 0.013 μM) and displays low affinity for hERG (IC50 >40 μM)[1].
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体内研究
(In Vivo) | CHK1-IN-3 significantly suppresses the tumor growth in Z-138 cell inoculated xenograft model as a single agent with body weight unaffected[1].
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
