Lurbinectedin-d3 是 Lurbinectedin 的氘代物。Lurbinectedin (PM01183) 是一种DNA小沟共价粘合剂，具有高效的抗肿瘤活性; 抑制 RMG1 和 RMG2 的IC50值分别为 1.25 和 1.16 nM。
| 生物活性 | Lurbinectedin-d3 is deuterium labeled Lurbinectedin. Lurbinectedin (PM01183) is aDNAminor groove covalent binder with potent anti-tumour activity; inhibits RMG1 and RMG2 cell growth withIC50values of 1.25 and 1.16 nM, respectively[1]. |
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | -20°C, protect from light, stored under nitrogen *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen) |
