Dot1L-IN-7 (compound 25) 是一种有效的、选择性的端粒沉默 1 样蛋白 (DOT1L) 抑制剂，IC50 为 1.0 μM。Dot1L-IN-7 选择性地杀死MLL-AF9，而对 E2A-HLF 细胞的生长没有任何影响。
| 生物活性 | Dot1L-IN-7 (compound 25) is a potent and selective disruptor of telomeric silencing 1-like protein (DOT1L) inhibitor with an IC50 of 1.0 μM. Dot1L-IN-7 selectively killed Mixed Lineage Leukemia (MLL)-AF9 without showing any effect on the growth of E2A-HLF cells[1]. |
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
