JAK-IN-5 is an inhibitor ofJAKextracted from patent US20170121327A1, compound example 283.

JAK^[1]

JAK-IN-5 (compound 1) (oral aspirate, 0.5 mg/mL, 50 μL ) inhibits STAT6 phosphorylation by 60% in IL-13-induced in lung tissue in a mouse model of pSTAT6 induction^[2].
JAK-IN-5 (compound 1) (oral aspirate, 0.1-1.0 mg/mL, 50 μL) inhibits 88% of BALF eosinophils in male C57 mice model ofAlternaria alternata-induced eosinophilic inflammation of the lung^[2].

474.57

C₂₇H₃₁FN₆O

2096999-92-5

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.