DPPY (compound 6) 是一种有效的PTK抑制剂,对 EGFR、BTK、JAK3 的IC50值分别为<10,<10,<10 nM。DPPY 对 B 细胞淋巴瘤细胞具有抗增殖活性。DPPY具有研究特发性肺纤维化(IPF)的潜力。
| 生物活性 | DPPY (compound 6) is a potentPTKinhibitor withIC50values of<10,<10,<10 nm forEGFR,BTK,JAK3, respectively. DPPY shows anti-proliferative activity against B-cell lymphoma cells. DPPY has the potential for the research of idiopathic pulmonary fibrosis (IPF)[1]. |
| IC50& Target[1] | JAK3 <10 nM (IC50) | EGFR <10 nM (IC50) | BTK <10 nM (IC50) |
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |