GS-829845 是 Filgotinib (HY-18300) 的主要活性代谢物。GS-829845 是一种JAK1抑制剂,但其效力比母体低约 10 倍且半衰期更长。
| 生物活性 | GS-829845 is a major, active metabolite of Filgotinib (HY-18300). GS-829845 is aJAK1preferential inhibitor but is approximately 10-fold less potent than the parent and with a longer half-life[1][2]. |
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |