ARTD10/PARP10-IN-1

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ARTD10/PARP10-IN-1

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

1708103-76-7

ARTD10/PARP10-IN-1 (compound 23) 是一种强效、非选择性的PARP抑制剂。ARTD10/PARP10-IN-1 靶向单 ADP 核糖转移酶ARTD7/PARP15，ARTD8/PARP14，ARTD10/PARP10和聚 ADP-核糖聚合酶-1 (ARTD1/PARP1)，IC₅₀分别为 1.7 μM，1.6 μM，0.8 μM，和 4.4 μM。

生物活性

ARTD10/PARP10-IN-1 (compound 23) is a potent and non-selectivePARPinhibitor, targeting to mono-ADP-ribosyltransferasesARTD7/PARP15,ARTD8/PARP14,ARTD10/PARP10and poly(ADP-ribose) polymerase-1 (ARTD1/PARP1) withIC₅₀s of 1.7 μM, 1.6 μM, 0.8 μM, and 4.4 μM, respectively^[1].

IC₅₀& Target^[1]

ARTD1/PARP1

4.4 μM (IC₅₀)

ARTD10/PARP10

0.8 μM (IC₅₀)

ARTD8/PARP14

1.6 μM (IC₅₀)

ARTD7/PARP15

1.7 μM (IC₅₀)

分子量

248.23

Formula

C₁₂H₁₂N₂O₄

CAS 号

1708103-76-7

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.