PARP10/15-IN-2

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PARP10/15-IN-2

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

PARP10/15-IN-2 (Compound 8h) 是一种有效的PARP10和PARP15双重抑制剂，对 PARP10 和 PARP15 的IC₅₀值分别为 0.15 μM 和 0.37 μM。PARP10/15-IN-2 能进入细胞并阻止细胞凋亡 (apoptosis)

生物活性

PARP10/15-IN-2 (Compound 8h) is a potentPARP10andPARP15dual inhibitor withIC₅₀values of 0.15 μM and 0.37 μM againstPARP10andPARP15, respectively. PARP10/15-IN-2 is able to enter cells and rescue cells fromapoptosis^[1].

IC₅₀& Target

PARP10

0.15 μM (IC₅₀)

PARP15

0.37 μM (IC₅₀)

分子量

286.26

性状

Solid

Formula

C₁₅H₁₁FN₂O₃

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)