ARTD10/PARP10-IN-2 (compound 19) 是一种强效、非选择性的PARP抑制剂。ARTD10/PARP10-IN-2 靶向单 ADP 核糖转移酶 (ARTD10/PARP10) 和聚 ADP-核糖聚合酶-1 (ARTD1/PARP1)，IC50分别为 2.0 μM，和 9.7 μM。
| 生物活性 | ARTD10/PARP10-IN-2 (compound 19) is a potent and non-selectivePARPinhibitor, targeting to mono-ADP-ribosyltransferasesARTD10/PARP10and poly(ADP-ribose) polymerase-1ARTD1/PARP1withIC50s of 2.0 μM, and 9.7 μM, respectively[1]. |
| IC50& Target[1] | ARTD1/PARP1 9.7 μM (IC50) | ARTD10/PARP10 2.0 μM (IC50) | ARTD8/PARP14 >20 μM (IC50) | ARTD7/PARP15 >20 μM (IC50) |
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
