CAS NO: | 126643-37-6 |
包装: | 100 μg |
市场价: | 4400元 |
生物活性 | KT5823, a selective the cGMP-dependent protein kinase (PKG) inhibitor with anKivalue of 0.23 μM, it also inhibitsPKAandPKCwithKivalues of 10 μM and 4 μM, respectively[1]. KT5823 is a staurosporine-related protein kinase inhibitor, increases thyroid-stimulating hormone-induced (Na+/I-symporter) NIS expression, and iodide uptake in thyroid cells[2]. KT5823 arrests cells after the G0/G1 boundary and causes increases in the levels ofapoptoticDNA fragmentation[3]. | |||||||||
IC50& Target[1] |
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分子量 | 495.53 | |||||||||
性状 | Solid | |||||||||
Formula | C29H25N3O5 | |||||||||
CAS 号 | 126643-37-6 | |||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | |||||||||
储存方式 |
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