SIRT5 inhibitor 4 (compound 11) 是一种有效的选择性SIRT5抑制剂，抑制 SIRT5 和其他 SIRT 亚型的IC50值分别为 26.4 μM 和 >400 μM。
| 生物活性 | SIRT5 inhibitor4 (compound 11) is a potent, selectiveSIRT5inhibitor withIC50values of 26.4 and >400μM forSIRT5and other SIRT subtype, respectively[1]. |
| IC50& Target[1] | SIRT5 26.4 μM (IC50) | SIRT1 ＞400 μM (IC50) | SIRT2 ＞400 μM (IC50) | SIRT3 ＞400 μM (IC50) | SIRT6 ＞400 μM (IC50) | SIRT7 ＞400 μM (IC50) |
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体外研究
(In Vitro) | SIRT5 inhibitor 4 (compound 11) (6-200 μM) stabilizes SIRT5 protein with a temperature shift of 1.8℃ in a dose-dependent manner[1].
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
