(S)-Mirtazapine ((S)-Org3770) 是 Mirtazapine 的 S(+)-对映异构体,在急性热伤害感受动物模型中具有促伤害感受的特性。(S)-Mirtazapine 是一种立体选择性5-HT2受体拮抗剂,在体内被 CYP2D6 和 CYP1A2 代谢。
生物活性 | (S)-Mirtazapine ((S)-Org3770) is a S(+)-enantiomer of Mirtazapine with pronociceptive properties in an animal model of acute thermal nociception. (S)-Mirtazapine is a stereoselective5-HT2receptorantagonist. (S)-Mirtazapine is metabolized by CYP2D6 and CYP1A2[1]. |
IC50& Target | 5-HT2Receptor | 5-HT3Receptor |
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运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Powder | -20°C | 3 years | | 4°C | 2 years | In solvent | -80°C | 6 months | | -20°C | 1 month |
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