CP-135807 是一种口服有效、选择性的5-HT1D激动剂 (IC50=3.1 nM)。CP-135807 介导中枢精神活性，可用于抗抑郁研究。
| 生物活性 | CP-135807 is an orally active and selective5-HT1Dagonist (IC50=3.1 nM), bovine). CP-135807 mediates central psychoactivity and can be used in antidepressant research[1][2]. |
| IC50& Target[1][2] | 5-HT1DReceptor 3.1 nM (IC50, rat) | 5-HT1DReceptor 33 nM (IC50, bovine) |
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体内研究
(In Vivo) | 鸽子被训练在一个固定比例的食物提供下啄一个键。CP-135807 (0.1 mg/kg; 肌肉注射; 单剂量) 则能够完全和剂量依赖地替代成年雄性卡诺鸽子的训练剂量[1]。
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
