WAY 629 hydrochloride

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CAS NO:

57756-44-2

WAY 629 hydrochloride 是一种有效的、选择性的5-HT_2C激动剂，对5-HT_2C和5-HT_2A的EC₅₀s 分别为426, 260000 nM。WAY 629 hydrochloride 降低摄食行为。

生物活性

WAY 629 hydrochloride is a potent and selective5-HT_2Cagonist withEC₅₀s of 426, 260000 nM for 5-HT_2Cand 5-HT_2A, respectively. WAY 629 hydrochloride decreases feeding behavior^[1]^[2].

IC₅₀& Target^[1]

5-HT_2CReceptor

426 nM (EC₅₀)

5-HT_2AReceptor

260000 nM (EC₅₀)

体内研究
(In Vivo)

WAY 629 hydrochloride (30 mg/kg; i.p.) 降低大鼠的进食行为^[1]。
WAY 629 hydrochloride (30 mg/kg; i.p.) 降低小鼠大脑中 NPY mRNA 的表达^[2]。

Animal Model:	WT mice^[2]
Dosage:	21 mg/kg
Administration:	I.p.
Result:	Decreased the expression of NPY mRNA.

分子量

262.78

Formula

C₁₅H₁₉ClN₂

CAS 号

57756-44-2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.