Synephrine hemitartrate

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CAS NO:

16589-24-5

Oxedrine hemitartrate

Synephrine (Oxedrine) hemitartrate，一种生物碱，是一种来自Citrus aurantium的α-adrenergic和β-adrenergic激动剂。Synephrine hemitartrate 是一种拟交感神经化合物，可用于减肥。

生物活性

Synephrine (Oxedrine) hemitartrate, an alkaloid, is anα-adrenergicandβ-adrenergicagonist derived from theCitrus aurantium. Synephrine hemitartrate is a sympathomimetic compound and can be used for weight loss^[1]^[2].

体内研究
(In Vivo)

Synephrine (1 mg/kg; oral gavage; for 8 days; PVL and BDL rats) significantly ameliorates the hyperdynamic state in both PVL and BDL rats. The portal venous pressure in PVL and BDL rats, portal tributary blood flow and cardiac index are significantly reduced, while mean arterial pressure and systemic as well as portal territory vascular resistance are enhanced by treatment of Synephrine^[2].

Animal Model:	Portal vein ligation (PVL) or bile duct ligation (BDL) rats^[2].
Dosage:	1 mg/kg per 12 hours
Administration:	Oral gavage; for 8 days
Result:	The portal venous pressure in PVL and BDL rats, portal tributary blood flow and cardiac index were significantly reduced, while mean arterial pressure and systemic as well as portal territory vascular resistance were enhanced.

分子量

242.26

Formula

C₉H₁₃NO₂.1/2C₄H₆O₆

CAS 号

16589-24-5

中文名称

辛弗林半酒石酸

结构分类

Alkaloids
Other Alkaloids

Phenols
Monophenols

来源

Plants
Rutaceae
Citrus reticulataBlanco

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.